A petition has been launched urging immediate action to clear rubbish from the A2 between Dover and Canterbury.
Anti-litter campaigners and residents have complained repeatedly about the mess strewn along the road, the principle route for visitors coming to Britain from Europe.
The petition has been posted on 38 Degrees, a campaigning website.
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“The problem has been escalating year on year and is now totally unacceptable potentially endangering the health of the public with bottles of urine being thrown from vehicles on to the roadside.
“The valiant efforts of volunteers are now at their limit and the situation overwhelming and fraught with danger trying to stem the tide of defecation being heaped on to our beautiful countryside.”
Lorry drivers are blamed for much of the mess along the route.
Campaigners have cleared rubbish from lay-bys in Bishopsbourne. And they have asked the authorities to close them because of mess left by drivers.
Canterbury City Council this week started a major clear-up of undergrowth at Faulkners Lane in Harbledown.
Piled with rubbish including urine-filled plastic bottles, the area is next to a lay-by off the A2.
The 38 degrees petition goes on: “Canterbury City Council, Kent County Council, Highways England and various other authorities have all been made aware of this appalling situation by outraged residents.
“Despite the constant stream of concern and level of complaint raised, it appears nothing is being done to properly address the situation and find a solution and a deterrent to it.
“This has got to stop and this petition calls upon all those in authority to act accordingly to bring an end to this intolerable blight on our lives.”
You can sign the petition here.